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Metabolic Syndrome: Sex-Related Cardiovascular Risk and Therapeutic Approach.

Abstract
The metabolic syndrome (MetS) is a cluster of risk factors for the development of cardiovascular diseases (CVD) and type 2 diabetes (T2DM). According to several meta-analyses, it has been shown that the cardiovascular (CV) risk conferred by the MetS is higher in women in comparison with men . There are many possible reasons to explain a higher CV risk in women with MetS: the most important differences can be attributed to distribution of central adiposity, lipid profile and hormones, but also differences in platelet biology and biochemistry play an important role. In this article we intended to review the evidence (or lack of evidence/biased information) regarding the distribution by gender of MetS components and associated CV risk, and to provide a consequent gender perspective to the treatment of MetS and CV risk.

PMID: 28699503 [Pubmed - Publisher]

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